Robert K Flamm Selected Research

7- (3- (2- amino- 1- fluoroethylidene)- 1- piperidinyl)- 1- cyclopropyl- 6- fluoro- 1,4- dihydro- 8- methoxy- 4- oxo- 3- quinolinecarboxylic acid

4/2012	Activity of JNJ-Q2, a new fluoroquinolone, tested against contemporary pathogens isolated from patients with community-acquired bacterial pneumonia.
12/2011	Efficacy of a new fluoroquinolone, JNJ-Q2, in murine models of Staphylococcus aureus and Streptococcus pneumoniae skin, respiratory, and systemic infections.
12/2011	Surveillance of JNJ-Q2 activity tested against Staphylococcus aureus and beta-hemolytic streptococci as a component of the 2010 SENTRY Antimicrobial Surveillance Program.

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Robert K Flamm Research Topics

Disease

70	Infections 07/2022 - 10/2003
19	Pneumonia (Pneumonitis) 03/2020 - 02/2011
17	Urinary Tract Infections (Urinary Tract Infection) 05/2021 - 06/2014
16	Bacterial Pneumonia 09/2020 - 12/2011
10	Intraabdominal Infections 05/2021 - 09/2014
9	Ventilator-Associated Pneumonia 07/2022 - 07/2014
9	Sepsis (Septicemia) 01/2021 - 12/2011
8	Respiratory Tract Infections (Respiratory Tract Infection) 05/2017 - 10/2003
6	Healthcare-Associated Pneumonia 07/2022 - 07/2014
6	Soft Tissue Infections 09/2016 - 04/2013
5	Pyelonephritis 05/2021 - 08/2018
4	Communicable Diseases (Infectious Diseases) 07/2020 - 01/2018
4	Bacteremia 01/2020 - 04/2016
3	Cross Infection (Nosocomial Infection) 11/2017 - 11/2016
2	Gonorrhea 10/2020 - 01/2016
2	Gram-Negative Bacterial Infections 01/2020 - 01/2017
2	Endocarditis 01/2019 - 03/2012
2	Osteomyelitis 04/2018 - 06/2017
2	Neoplasms (Cancer) 01/2018 - 03/2017
2	Body Weight (Weight, Body) 03/2012 - 12/2011
1	Cystitis 10/2020
1	Bacterial Endocarditis 01/2019
1	Gram-Positive Bacterial Infections 06/2018
1	Bacterial Infections (Bacterial Infection) 01/2017
1	Diabetic Foot 03/2015
1	Ulcer 03/2015
1	Meningitis 03/2014

Drug/Important Bio-Agent (IBA)

20	Ceftaroline FDA Link 12/2018 - 09/2012
15	ceftazidime drug combination avibactamIBA 03/2020 - 06/2014
11	tazobactam drug combination ceftolozaneIBA 05/2021 - 06/2014
10	Anti-Bacterial Agents (Antibiotics)IBA 06/2019 - 09/2012
9	oritavancinIBA 01/2019 - 05/2014
8	ceftobiproleIBA 07/2022 - 01/2010
8	dalbavancinIBA 01/2019 - 05/2015
6	Cephalosporins (Cephalosporin Antibiotics)IBA 07/2022 - 08/2016
6	omadacyclineIBA 12/2021 - 01/2017
6	Meropenem (Merrem)FDA LinkGeneric 10/2020 - 05/2011
6	telavancin FDA Link 01/2020 - 01/2015
5	Metronidazole (Metric)FDA LinkGeneric 05/2021 - 01/2017
5	ceftobiprole medocarilIBA 01/2020 - 01/2010
5	LactamsIBA 06/2019 - 12/2015
4	ProdrugsIBA 01/2020 - 01/2010
4	Carbapenems (Carbapenem Antibiotics)IBA 01/2019 - 02/2011
4	Vancomycin FDA LinkGeneric 07/2013 - 01/2010
3	delafloxacinIBA 12/2020 - 10/2003
3	Anti-Infective Agents (Microbicides)IBA 07/2020 - 03/2015
3	Daptomycin FDA Link 01/2020 - 03/2012
3	tedizolidIBA 01/2020 - 01/2019
3	CoagulaseIBA 07/2019 - 05/2015
3	FluoroquinolonesIBA 06/2019 - 12/2011
3	Fosfomycin FDA Link 02/2019 - 07/2014
3	Cefepime (Maxipime)FDA LinkGeneric 01/2019 - 01/2017
3	Ceftazidime (Fortum)FDA LinkGeneric 01/2019 - 06/2014
3	Amikacin (A.M.K)FDA LinkGeneric 10/2018 - 07/2014
3	Doripenem FDA Link 08/2018 - 02/2011
3	Linezolid (Zyvox)FDA Link 07/2013 - 01/2010
3	7- (3- (2- amino- 1- fluoroethylidene)- 1- piperidinyl)- 1- cyclopropyl- 6- fluoro- 1,4- dihydro- 8- methoxy- 4- oxo- 3- quinolinecarboxylic acidIBA 04/2012 - 12/2011
2	iclaprim (AR 100)IBA 01/2021 - 01/2018
2	gepotidacinIBA 10/2020 - 01/2016
2	Topoisomerase InhibitorsIBA 10/2020 - 01/2016
2	lefamulinIBA 01/2019 - 01/2016
2	Tazobactam Drug Combination Piperacillin (Zosyn)FDA LinkGeneric 09/2018 - 08/2016
2	Gentamicins (Gentamicin)FDA LinkGeneric 09/2018 - 09/2016
2	Tigecycline (Tygacil)FDA Link 06/2018 - 06/2013
2	Pharmaceutical PreparationsIBA 11/2017 - 07/2014
2	cefepime-zidebactamIBA 01/2017 - 01/2017
2	MacrolidesIBA 01/2017 - 02/2002
2	Methicillin (Metin)FDA Link 12/2011 - 01/2010
1	SPR741IBA 04/2020
1	Polymyxin B (Aerosporin)FDA LinkGeneric 01/2020
1	AminoglycosidesIBA 06/2019
1	tebipenemIBA 01/2019
1	PleuromutilinsIBA 01/2019
1	tedizolid phosphateIBA 01/2019
1	enmetazobactamIBA 01/2019
1	Colistin (Coly-Mycin)FDA Link 09/2018
1	Levofloxacin (Levaquin)FDA Link 09/2018
1	plazomicinIBA 01/2018
1	murepavadinIBA 01/2018
1	Carrier Proteins (Binding Protein)IBA 01/2018
1	Tazobactam FDA LinkGeneric 10/2017
1	zidebactamIBA 01/2017
1	polymyxin B drug combination bacitracin (Polysporin)FDA Link 09/2016
1	Fusidic Acid (Fucithalmic)IBA 09/2016
1	Neomycin FDA LinkGeneric 09/2016
1	retapamulin FDA Link 09/2016
1	Mupirocin (Bactroban)FDA LinkGeneric 09/2016
1	solithromycinIBA 01/2016
1	meropenem and vaborbactamIBA 01/2016
1	carbapenemaseIBA 01/2016
1	Peptides (Polypeptides)IBA 03/2015
1	CationsIBA 03/2015
1	pexigananIBA 03/2015
1	avibactamIBA 04/2014
1	Penicillins (Penicillin)FDA Link 03/2014

Therapy/Procedure

6	Mechanical Ventilators (Ventilator) 09/2020 - 11/2016
3	Therapeutics 06/2019 - 01/2017
2	Nebulizers and Vaporizers (Inhaler) 07/2014 - 07/2014
1	Lasers (Laser) 03/2016
1	Artificial Respiration (Mechanical Ventilation) 07/2014